Mark A. Goldsmith, M.D., Ph.D.
Mark Goldsmith joined Third Rock Ventures as a venture partner in 2012 and was appointed a partner in 2013. He brings more than 25 years of experience in the life sciences. Mark plays an instrumental role in the ideation, development and leadership of new companies. He has been integral in launching and building several of our portfolio companies, playing key leadership roles:
- Founding president, member of the board and chief executive officer of REVOLUTION Medicines
- Chairman of the board and former interim chief executive officer of Nurix
- Former board member and interim chief executive officer of Global Blood Therapeutics
- Chairman of the board and former chief executive officer of Constellation Pharmaceuticals
- Board member of Igenica Biotherapeutics
Prior to joining Third Rock, Mark was president and chief executive officer of Constellation Pharmaceuticals, a leading biopharmaceutical company in the field of epigenetics and a Third Rock portfolio company. He led the development of an industry-leading strategic alliance with Genentech and remains active in the company as its chairman. Before Constellation, Mark held senior executive positions in the biotechnology industry and academia. He was a senior executive-in-residence at Prospect Venture Partners, a leading healthcare venture capital firm, chief executive officer of Cogentus Pharmaceuticals and senior vice president of Genencor International’s healthcare division. Before entering the private sector, Mark led a productive medical research laboratory at the Gladstone Institute of Virology and Immunology, and he practiced medicine on the faculty of the University of California, San Francisco School of Medicine and at San Francisco General Hospital. He also served as a consultant to leading pharmaceutical and biotechnology companies. Mark holds an A.B. in biology from Princeton University, earned his M.D. and Ph.D. in microbiology and immunology from the University of California, San Francisco, and conducted postgraduate medical training at the Brigham and Women's Hospital/Harvard Medical School and the University of California, San Francisco.
As a teenager, Mark performed magic at children’s birthday parties.