Mark A. Goldsmith, M.D., Ph.D.

Venture Partner

Mark Goldsmith joined Third Rock Ventures as a venture partner in 2012 and was appointed a partner in 2013. He brings more than 25 years of experience in the life sciences. Mark plays an instrumental role in the ideation, development and leadership of new companies. He has been integral in launching and building several of our portfolio companies, playing key leadership roles:

  • Founding president, member of the board and chief executive officer of REVOLUTION Medicines
  • Chairman of the board and former interim chief executive officer of Nurix
  • Former board member and interim chief executive officer of Global Blood Therapeutics
  • Chairman of the board and former chief executive officer of Constellation Pharmaceuticals
  • Board member of Igenica Biotherapeutics

Prior to joining Third Rock, Mark was president and chief executive officer of Constellation Pharmaceuticals, a leading biopharmaceutical company in the field of epigenetics and a Third Rock portfolio company. He led the development of an industry-leading strategic alliance with Genentech and remains active in the company as its chairman. Before Constellation, Mark held senior executive positions in the biotechnology industry and academia. He was a senior executive-in-residence at Prospect Venture Partners, a leading healthcare venture capital firm, chief executive officer of Cogentus Pharmaceuticals and senior vice president of Genencor International’s healthcare division. Before entering the private sector, Mark led a productive medical research laboratory at the Gladstone Institute of Virology and Immunology, and he practiced medicine on the faculty of the University of California, San Francisco School of Medicine and at San Francisco General Hospital. He also served as a consultant to leading pharmaceutical and biotechnology companies. Mark holds an A.B. in biology from Princeton University, earned his M.D. and Ph.D. in microbiology and immunology from the University of California, San Francisco, and conducted postgraduate medical training at the Brigham and Women's Hospital/Harvard Medical School and the University of California, San Francisco.

As a teenager, Mark performed magic at children’s birthday parties.

Administrative Support

Marcia Hemphill
Office Manager - West Coast and Executive Assistant
mhemphill@thirdrockventures.com
(415) 766-3638

Associated Portfolio Companies

Partners

Alexis Borisy

Partner

Abbie Celniker, Ph.D.

Partner

Neil Exter

Partner

Kevin Gillis

Partner/Chief Financial Officer

Charles Homcy, M.D.

Partner

Sarah Larson

Partner/Chief Human Resources Officer

Mark Levin

Partner

Craig Muir

Partner/Chief Technology Officer

Cary Pfeffer, M.D.

Partner

Kevin Starr

Partner

Robert Tepper, M.D.

Partner

Venture Partners

Frank T. Gentile, Ph.D.

Venture Partner

Mark A. Goldsmith, M.D., Ph.D.

Venture Partner

Perry Karsen

Venture Partner

Christoph Lengauer, Ph.D.

Venture Partner

Philip Reilly, M.D., J.D.

Venture Partner

Stephen Sherwin, M.D.

Venture Partner

Jeffrey Tong, Ph.D.

Venture Partner

Barbara Weber, M.D.

Venture Partner

Entrepreneurs-In-Residence

Jason Coloma, Ph.D.

Entrepreneur-in-Residence

Keith Dionne, Ph.D.

Entrepreneur-in-Residence

Jeffrey Finer, M.D., Ph.D.

Entrepreneur-in-Residence

Alexandra Glucksmann, Ph.D.

Entrepreneur-in-Residence

Eric Green, M.D., Ph.D.

Entrepreneur-in-Residence

Brian Jones, Ph.D.

Entrepreneur-in-Residence

Robert Kamen, Ph.D.

Entrepreneur-in-Residence

Leon Murphy, Ph.D.

Entrepreneur-in-Residence

Glenn Pierce, M.D., Ph.D.

Entrepreneur-in-Residence

Laurence Turka, M.D.

Entrepreneur-in-Residence

Domain Experts

Karina Chmielewski

Senior Director, Platform Operations

Dina Ciarimboli

General Counsel

Cynthia Clayton

Head of Communications

John Keilty

General Manager, Platform Operations

Principals and Associates

Brian Albrecht, Ph.D.

Principal

Tim Funnell, DPhil.

Principal

Claire Mazumdar, Ph.D., M.B.A.

Associate

Melissa McCracken, Ph.D.

Associate

Kelly Moynihan, Ph.D.

Associate

Travis Murdoch, M.D.

Principal

Vyas Ramanan, Ph.D.

Associate

Dominique Verhelle, Ph.D., M.B.A.

Principal

Recruiting

Andrea DiMella

Recruiting Director

Tracy Nicholson

Recruiting Director

Chris Robinson

Vice President, Recruiting

Administrative

Zoe Angell

Executive Assistant

Megan Graziano

Manager of Operations and Administration

Linda Heath

Executive Assistant

Marcia Hemphill

Office Manager - West Coast and Executive Assistant

Rhea Kappa

Receptionist/Administrative Assistant

Maribel Laboy

Executive Assistant

Megan Lamb

Executive Assistant

Ian Miller

Administrative Assistant

Corey O’Keeffe

Event Planner & Communications

Angelo Severino

Executive Assistant

Laura Vitale

Administrative Assistant

Tracy Williams

Executive Assistant

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